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butabarbital will minimize the extent or impact of nifedipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.butabarbital will decrease the extent or result of lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.Teniposide: Barbiturates may minimize the serum focus of Ten